Noble Panacea

The Overnight Mask

A luxurious nighttime mask that works in three phases—detox, repair, and replenish—to reveal revitalized, radiant skin by morning.

$326.00

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Product details

A sophisticated nighttime treatment, this sleep mask is designed to work in synergy with your skin’s natural biorhythms. Powered by Noble Panacea’s patented OSMV™ Technology, this mask delivers a programmed sequence of active ingredients through the skin’s detox, repair, and regeneration phases overnight. The result: a high-efficacy formula that deeply hydrates, strengthens, and rebalances—revealing skin that is visibly smoother, plumper, and more radiant by morning.


The science-driven formula restores barrier function, boosts collagen production, and visibly softens signs of fatigue, stress, and aging. Ideal for use 1–2 times a week, this mask is the final step in a truly elevated nighttime ritual.


INSIDE THE FORMULA

  • OSMV™ Technology: Allows precise, time-controlled ingredient delivery in harmony with the skin’s nightly regeneration cycle.
  • PHA: Gently exfoliates and detoxifies while calming inflammation and promoting even tone.
  • Pre, Pro, and Post Biotics: Support a balanced microbiome to strengthen skin’s natural defense.
  • Retinol: Boosts collagen and cell turnover, visibly improving texture and fine lines.
  • Peptides: Enhance skin firmness and elasticity while reinforcing structure.
  • Ceramide NP: Fortifies the moisture barrier and improves skin resilience.
  • Dual-Weight Hyaluronic Acid: Offers both deep and surface hydration for lasting plumpness and glow.


CLINICAL RESULTS
After four (4) usages:

  • 100% felt skin looked replenished, energized, and healthy-looking
  • 97% said skin felt firm and plumped
  • 94% reported reduced redness and irritation


After eight (8) usages:

  • 97% said skin looked luminous and radiant
  • 91% saw a reduction in dark spots and pigmentation
  • 89% noted an improvement in the appearance of deep wrinkles


*Based on clinical trials tested on 35 women 

how to use

Apply the Chronobiology Sleep Mask 1 to 2 times a week, or as needed, to clean, dry skin on the face and neck. Use as the final step in your evening skincare ritual before sleeping. Allow the formula to fully absorb overnight for maximum benefits, and follow with SPF the next day.

ingredients

Water/Eau/Aqua, Argania Spinosa (Argan) Kernel Oil, Glycerin, Oligosaccharide Fatty Acid Esters (OSMV), Squalane, Ascorbyl Glucoside, Lactobacillus Ferment, Sucrose Stearate, Cetearyl Alcohol, Niacinamide, Potassium Cetyl Phosphate, Vitis Vinifera (Grape) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Dipalmitoyl Hydroxyproline, Alpha-Glucan Oligosaccharide, Propanediol, Rosa Damascena (Rose) Flower Water, Aloe Barbadensis Leaf Juice, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Stearyl Alcohol, Lactic Acid, Opuntia Ficus-Indica (Prickly Pear) Seed Oil, Nigella Sativa (Black Cumin) Seed Oil, Ceramide NP, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Retinol, Gluconolactone, Persea Gratissima (Avocado) Oil, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-38, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-9, Centella Asiatica (Gotu Kola) Leaf Extract, Magnesium Ascorbyl Phosphate, Glycolic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Bakuchiol, Caffeine (Coffea Arabica), Panax Ginseng Root Extract, Acetyl Glutamine, Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Xanthan Gum, Carnitine, Rice Amino Acids, Vitis Vinifera (Grape) Seed Extract, Ascorbyl Tetraisopalmitate, Glyceryl Linoleate, Phytic Acid, Ascorbyl Palmitate, Panthenol, Tocopherol, Tocopheryl Acetate, Glyceryl Linolenate, Oryza Sativa (Rice) Bran Extract, Helianthus Annuus (Sunflower) Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Ubiquinone, Potassium Hydroxide, Phospholipids, Bacillus/Folic Acid Ferment Filtrate Extract, Hydroxypropyl Cyclodextrin, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium Benzoate  

Editor's Note

The formula is smart. Circadian-rhythm-smart. The patented OSMV™ technology works with your body to repair and balance the microbiome.