Board-certified dermatologic surgeon Dr. Antony Nakhla developed this advanced overnight treatment for experienced retinoid users seeking transformative results. Formulated with RetinalXR™—a proprietary, microencapsulated retinal technology that delivers 250% more potency than standard retinol– this cream minimizes irritation through time-release absorption.

Let the formula work while you sleep. Wake up with smoother texture, reduced appearance of fine lines and wrinkles, and brightened dark spots. Peptide-rich Plasma®, Eighth Day’s signature complex of 24 bioidentical peptides, amino acids, and growth factors, supports skin’s natural renewal processes for visible overnight regeneration. The formula’s age-defying power activates collagen production and supports long-term skin vitality. Expect firmer, clearer, more luminous skin with continued use.

INSIDE THE FORMULA

RetinalXR™: A potent, microencapsulated retinal with 250% the strength of retinol to resurface skin, improve clarity, and reduce signs of aging
Peptide-rich Plasma®: 24 bioidentical peptides and growth factors to support repair and cellular renewal
Bakuchiol: A plant-based retinol alternative that firms, smooths texture, and reduces dark spots
GGA (Teprenone): Supports skin cell longevity and helps protect against environmental and DNA damage

CLINICAL RESULTS

100% agree the Night Cream delivers professional-grade results
97% showed significant improvement in firmness
94% showed a reduction in fine lines and wrinkles

Hand & Foot Creams