For those in search of something more intensive, there have been significant strides made in the treatment realm. Cellulaze, which the FDA approved a few years ago, uses laser energy (applied beneath the skin surface) to soften the fibrous bands of connective tissue, melt fat and tighten. The doctors who have used it claim that cellulite doesn’t reoccur after the procedure, but it can be costly (around $5,000). Another option is mesotherapy, a treatment that’s wildly popular throughout Europe and Asia, but that still hasn’t caught on in the US (it remains unapproved by the FDA here). Mesotherapy consists of micro-injections of substances like vitamins, minerals, amino acids, or enzymes. “Our average needles in medicine are about 13 millimeters, but in mesotherapy they don’t go deeper than four to six millimeters,” explains Madhere. “You are going superficial to mid-dermis where a lot of the collagen and micro-vasculature resides, and people who perform it believe it has a tightening effect on the skin.” Though it may offer a slight improvement for cellulite, Engelman cautions that mesotherapy also carries risks like swelling, infection, and irregular contours. Madhere and Dr. Haideh Hirmand are both excited about the arrival of Cellfina, a new quickie (an hour or less) treatment that releases the fibrous bands in dimpled areas using a device that mimics the surgical process of subcision. “You place it over the area after numbing it, and it releases a blade that cuts the bands very quickly and efficiently, allowing you to do more in a shorter amount of time,” says Madhere. “If you have stage 1 cellulite [aka, orange peel skin] it won’t be helpful, but for those with stage 2, meaning plenty of dimples, it will be a great option.” And Dr. Joshua Zeichner reports that another, as yet unnamed, treatment on the horizon, presented at the AAD conference this year, is an injectable that will actually melt fibrous bands away rather than cutting them.